slideshare chemistry of nucleic acids

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January 8, 2018

slideshare chemistry of nucleic acids

Clipping is a handy way to collect important slides you want to go back to later. Isolation and Purification of Genomic DNA. OUT LINE • INTRODUCTION • NUCLEOSIDE • NUCLEOTIDE • DNA STRUCTURE • RNA STRUCTURE … Chemistry of Nucleic Acids He reported finding a weakly acidic substance of unknown function in the nuclei of human white blood cells, and named this material \"nuclein\". Objectives By the end of lecture the student should: Define nucleic acids. Elemental analysis of nucleic … • Nucleic acids, which include DNA (deoxyribonucleic acid) and RNA (ribonucleic acid), are made from monomers known as nucleotides. See our Privacy Policy and User Agreement for details. •Nucleic acids are polymers that consist of nucleotide residues. They are composed of nucleotides, which are the monomers made of three components: a 5-carbon sugar, a phosphate group and a nitrogenous base.If the sugar is a compound ribose, the polymer is RNA (ribonucleic acid… Nucleic Acid Chemistry Dr: Hussein abdelaziz. Viruses can be grouped … In the 1920's nucleic acids were found to be major components of chromosomes, small gene-carrying bodies in the nuclei of complex cells. A related type of nucleic acid, called ribonucleic acid … Professor and Head Nitrogen base Both DNA and RNA have four nitrogen bases available to construct nucleotides. Jaipur, India A and G are categorized as purines, and C, T, and U … • These are of two types: • Deoxyribonucleic acid (DNA) • Ribonucleic acid … Genomic DNA is found in the nucleus of all living cells with … Subsequent work showed that they are polymers, and the monomeric subunit of nucleic acids was termed a nucleotide. • Huge organic molecules that contains C, H, O, N, & P. • Nucleic acid is a polymer of NUCLEOTIDE held by 3’ and 5’ phosphate bridges. He found it behaved as an acid, so the material was renamed nucleic acid. Nuclein is the material found in the nucleus, consisting mainly of nucleic acids, protein, and phosphoric acid. Hence nucleic acids … A free online book on the chemistry and biology of nucleic acids, written by Prof. Tom Brown and Dr Tom Brown (Jnr). Phosphate group 3. The structure of … Each nucleotide has three components: 1. An … Title: nucleic acid 1 NUCLEIC ACID 2 NUCLEIC ACID. Both DNA (deoxyribonucleic acid) and RNA (ribonucleic acid) are polymers of individual nucleotides. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid … 4-1.2. Five-carbon-ring sugar (deoxyribose or ribose) 2. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Gupta In 1889, Richard Altmann investigated the chemical properties of nuclein. Primary Structure of Nucleic Acids Nucleotides are joined together through the phosphate group of one nucleotide connecting in an ester linkage to the OH group on the third carbon atom of the sugar unit of a second nucleotide. Clipping is a handy way to collect important slides you want to go back to later. THE NUCLEIC ACIDS DR SAKINA ROOHI MBBS. Components Components are similar to its monomer (nucleotide): 1. DNA is the cellular molecule that contains instructions for the performance of all cell … Looks like you’ve clipped this slide to already. Viral infections can pose a mild risk to our health, like the common cold, or a threat to our lives, like an HIV infection. Definition Nucleic acid may be defined as the polymer of nucleotides connected by 3’-5’ phosphodiester bond 8. Nucleic acids play a significant role in this process. Nucleic acids are the most important macromolecules for the continuity of life.They carry the genetic blueprint of a cell and carry instructions for the functioning of the cell. (DNA and RNA). COMPONENTS OF NUCLEIC ACIDS: • Nucleic acids are polymers of Nucleotides NUCLEOTIDES :- 1. Nucleic acids are known as information molecules They store genetic information The nucleic acids are of two types: • Deoxyribonucleic acid (DNA) • Ribonucleic acid … A Nucleic Acid is made up of Nucleotides which are its monomers. If you continue browsing the site, you agree to the use of cookies on this website. Metabolism of Purine & Pyrimidine nucleotide, Purine pyrimidine metabolism and disorder, Biomolecular ligand-receptor-binding-studies-theory, Central University of Gujarat, Gandhinagar, Nucleic acid chemistry for 1st year medical 5 04-2016, No public clipboards found for this slide. Both DNA and RNA are large molecules of successive nucleotides bonded to t… Nucleic Acids 1. You can change your ad preferences anytime. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Nucleoside, a structural subunit of nucleic acids, the heredity-controlling components of all living cells, consisting of a molecule of sugar linked to a nitrogen-containing organic ring compound.In the most … NUCLEIC ACIDS :
3. Nucleic Acid • First discovered in the nuclei of cells. Components of nucleic acids Nucleotide bases Nucleic acids are the acidic component of nuclei, first identified by Meischer in the late 19th century. Unlike in nucleic acid nucleotides, singular cyclic nucleotides are formed whe… Nucleic acids … Individual phosphate molecules repetitively connect the sugar-ring molecules in two adjacent nucleotide monomers, thereby connecting the nucleotide monomers of a nucleic acid end-to-end into a long chain. Nucleic acid … The first isolation of what we now refer to as DNA was accomplished by Johann Friedrich Miescher circa 1870. If you continue browsing the site, you agree to the use of cookies on this website. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Nitrogenous base + a pentose sugar + a phosphate group. DNA, organic chemical of complex molecular structure found in all prokaryotic and eukaryotic cells. Deoxyribonucleic acid (DNA) encodes the information the cell needs to make proteins. It codes genetic information for the transmission of inherited traits. Department of Biochemistry Separation of the nucleic acids from other cellular components • Purification of nucleic acids . Review the following table for similarities and differences between DNA and RNA. Nucleic Acids 22.1 Types of Nucleic Acids 22.2 Nucleotides: Building Blocks of Nucleic Acids 22.3 Primary Nucleic Acid Structure 22.4 The DNA Double Helix 22.5 Replication of DNA Molecules 22.6 Overview of Protein Synthesis 22.7 Ribonucleic Acids Chemistry … Viruses are everywhere -- and abundant. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. National Institute of Medical Sciences Oligonucleotide synthesis is the chemical synthesis of relatively short fragments of nucleic acids with defined chemical structure ().The technique is extremely useful in current laboratory practice because … • Each nucleotide has three components: a 5 … Structure of Nucleic Acids. You can change your ad preferences anytime. The molecular structure of nucleic acid store this information in the coded form. See our User Agreement and Privacy Policy. R.C. Typically, a nucleic acid is a large molecule made up of a string, or “polymer,” of units called “nucleotides.” All life on Earth uses nucleic acids as their medium for recording hereditary information – that is nucleic acids … A single nucleotide is made up of three components: a nitrogen-containing base, a five-carbon sugar (pentose), and at least one phosphate group With all three joined, a nucleotide is also termed a “nucleoside phosphate”. Nucleic acid is an important class of macromolecules found in all cells and viruses. DNA Structure. 2. Three of the nitrogen bases are the same. Gupta Professor and Head Department of Biochemistry National Institute of Medical Sciences Jaipur, India Chemistry of Nucleic Acids (DNA and RNA) 2. See our User Agreement and Privacy Policy. Illustrate structure of nucleotides. A … If you continue browsing the site, you agree to the use of cookies on this website. … Each nucleic acid contains four of five possible nitrogen-containing bases: adenine (A), guanine (G), cytosine (C), thymine (T), and uracil (U). Nucleotides are held together by peptide bonds. 1. Nucleic Acids in Chemistry and Biology: G. Michael Blackburn ... www.amazon.com › ... › Chemistry › Polymers & Macromolecules 'The text is well written, clearly laid out, with good illustrations, and an emphasis on how the chemistry of nucleic acids explains the biology of nucleic acids. Nucleic acid metabolism is the process by which nucleic acids (DNA and RNA) are synthesized and degraded.Nucleic acids are polymers of nucleotides.Nucleotide synthesis is an anabolic mechanism generally involving the chemical reaction of phosphate, pentose sugar, and a nitrogenous base.Destruction of nucleic acid … Nucleic acid chemistry 1. They perform a … Now customize the name of a clipboard to store your clips. Know the three chemical components of a nucleotide: a monosaccharide residue (either ribose or deoxyribose), at least one phosphate … 1 Chapter 14 Lecture Notes: Nucleic Acids Educational Goals 1. Nucleic Acids Book. The functions of nucleic acids have to do with the storage and expression of genetic information. Nucleic acids are long-chain polymeric molecules, the monomer (the repeating unit) is known as the nucleotides and hence sometimes nucleic acids are referred to as polynucleotides Introduction:
Frederic Miesher in 1869, isolated an acidic compound from the nuclear material of SALMON sperms, and named it as NUCLIEN which is now called NUCLEIC ACID.
Jones in 1920 proved the fact there are two types of nucleic acids, i.e., Deoxyribo nucleic acid (DNA) and Ribonucleic acid … BISSMILLAH AHRAHMAN AR-RAHEEM.
2. See our Privacy Policy and User Agreement for details. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Chapter 22. 1. List functions of nucleotides. Indian medical graduate - goals, roles and competencies, Acid base balance - Regulation of pH of body fluids, No public clipboards found for this slide. Although nucleic acid chemistry appears to be a mature part of organic and bioorganic chemistry, the many questions that are still being raised by research in biology and chemical biology give sufficient motivation to continue to synthesize new nucleic acid probes and thereby further develop nucleic acid chemistry… •Each nucleotide is put together from three building blocks: 1) phosphoric acid 2) a monosaccharide 3) an organic base . 1) Phosphoric Acid … Nucleic acids are biological macromolecules ; They are members of a family of biopolymers essential for life, and include DNA and RNA ; nucleic acids function in encoding, transmitting and expressing genetic information. In each individual nucleotide there is a Phosphate, sugar, and Nitrogenous base. The book is ideal for chemistry and biology students and also … Nucleic acids are the biopolymers, or large biomolecules, essential to all known forms of life.The term nucleic acid is the overall name for DNA and RNA. Now customize the name of a clipboard to store your clips. R.C. If you continue browsing the site, you agree to the use of cookies on this website. Nucleic acids … Looks like you’ve clipped this slide to already. Such stored information is known to control the inherited characteristics … A few years later, Miescher separated nuclein into protein and nucleic acid components. We will now turn to the chemistry of nucleic acids. M.D 2. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Expression of genetic information work showed that they are polymers, and to provide with... This information in the nuclei of cells make proteins nucleotide there is a handy way to collect important you! ) a monosaccharide 3 ) an organic base DNA and RNA have four nitrogen bases available to construct nucleotides NUCLEOSIDE. Educational Goals 1 the chemical properties of nuclein and Head Department of Biochemistry National of! 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